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  • Nisco Encapsulation Unit – Var J30
Nisco Encapsulation Unit – Var J30

Nisco Encapsulation Unit – Var J30

The VARJ30 is the aerodynamically assisted jetting equipment showed on the figure below. The product enters through a central needle. The exit orifice, which is centrally in line with the axis of the needle, has been counter sunk externally. The counter sunk leads to the aero dynamical effect that the jet has the smaller diameter when it is passing the orifice than the needle. The needle is enclosed in a pressure chamber with an exit through the orifice. The size of the drops is determined by the product flow rate and the pressure inside the chamber. The product flow rate is typically controlled by a hyprecision syringe to be connected to the product nozzle. The pressure in the pressure chamber is controlled by the Nisco Pressure controller. The pressure sensor is installed in the HMI* control console. The pressure set-point can be entered via touch screen.


Encaptsultaion

principle of aerodynamically assisted jetting

Typical bead distribution: The beads were made with the nominal sized unit of 350 μm, resulting peak at 20 μm

Var J30The bead generator with coaxial airflow is basically made of stainless steel 1.4435 (equivalent 316L) and can withstand most chemicals and high temperatures, which make the unit very suitable for any disinfecting/ cleaning method including autoclave cleaning. As gaskets O-rings made of EPDM are delivered. For pharmaceutical or medical applications the required material certificates are available.

The VARJ30 is supplied two nozzle sizes, (available 100, 150, 200,250, 350, 400, 500, 600, 700, 800, 900, 1000 mm). This unique technology has the following advantages: The reachable smallest particle is approximately 1:10 smaller than the needle diameter, depending on the physical properties of the product and on the requirements in regard of the particle homogeneity even smaller. So you can achieve very small particles with a minimised danger of clogging. So near homogenous particles around 10 micrometer are now in the reach with the VARJ30.

Continuation Encapsulation Unit – VARJ30

The technology as it is applied in our VARJ30 has been published 1980 by Prof. Peter Walzel.
The concept of flow focussing was there since the dates going back to as far or even or further back to the 1960's

1968:
LLoyd Spielman and Simon L. Goren
Improving Resolution in Coulter Counting by Hydrodynamic Focusing
Department of Chemical Engineering, University of California, Berkley
Journal of Colloid and Interface Science 26, 176-182

1983
The concept has since been used heavily in the cytometry industry. Just to mention one example:
US Patent 1983 4,408,877 vice for hydrodynamic focussing of a particle-suspension in a liquid flow cytophotometer

1980
P. Schmidt and P. Walzel,
Zerstäuben von Flüssigkeiten
Chem.-Ing.-Tech, 52 (1980) Nr. 4, S. 304-311.

1990
P. Walzel,
Zerstäuben von Flüssigkeiten
Chem.-1ng.-Tech. 62 (1990) Nr. 12, S. 983-994
VCH Verlagsgesellschaft mbH, D-6940 Weinheim, 1990

1997
A.M. Ganan Calvo and A. Barrero
A Novel Pneumatic Technique to Generate Steady
Capilary Microjets Aerosol Sci Vol 30, No. 1 pp. 118-125 1999

Since 1997 there were a lot of publications by various authors. There are also numerous current patents on the field of flow focussing. They were all published later than the articles listed above. For example US Patent 619953 by University Seville followed by numerous patents the following years.